In the largest study to date on myocarditis deaths related to COVID-19 vaccination, researchers found that 100 people in England died of myocarditis soon after receiving a COVID-19 vaccine.

The study, published Aug. 22 in the American Heart Association’s journal, Circulation, found more than half (51) of the deaths occurred within 1 to 28 days after receiving a dose of the AstraZeneca vaccine and just under half (49) of the deaths occurred within 1 to 28 days after a dose of the Pfizer-BioNTech vaccine.

The AstraZeneca vaccine, not authorized for use in the U.S., uses an adenovirus technology similar to that used by Johnson & Johnson’s (J&J), or Janssen) COVID-19 vaccine, which is authorized for emergency use in the U.S. Prior research has underscored the risk of fatal myocarditis associated with the mRNA technology used in the Pfizer and Moderna COVID-19 vaccines. This study showed the technology used in AstraZeneca’s vaccine poses a similar risk.

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