Understanding SARS-CoV-2 transmission within and among communities is critical for tailoring public health policies to local context. However, analysis of community transmission is challenging due to a lack of high-resolution surveillance and testing data. Here, using contact tracing records for 644,029 cases and their contacts in New York City during the second pandemic wave, we provide a detailed characterization of the operational performance of contact tracing and reconstruct exposure and transmission networks at individual and ZIP code scales.
We find considerable heterogeneity in reported close contacts and secondary infections and evidence of extensive transmission across ZIP code areas. Our analysis reveals the spatial pattern of SARS-CoV-2 spread and communities that are tightly interconnected by exposure and transmission. We find that locations with higher vaccination coverage and lower numbers of visitors to points-of-interest had reduced within- and cross-ZIP code transmission events, highlighting potential measures for curtailing SARS-CoV-2 spread in urban settings.
Within metropolitan areas, infection risk and disease burden due to SARS-CoV-2, the causative agent of COVID-19, are characterized by spatial heterogeneity at neighborhood scales. Communities with substantial local infections can sustain the spread of SARS-CoV-2, seed infections in interconnected neighborhoods, and spark resurgences of cases following the relaxation of non-pharmaceutical interventions (NPIs), such as masking and social distancing.