In a recent study published in the Emerging Infectious Diseases journal, researchers at Madigan Army Medical Center assessed the characteristics of monkeypox infection in a patient vaccinated against smallpox.

In Summer 2022, the Centers for Disease Control and Prevention (CDC) initiated an emergency response after the outbreak of monkeypox infections across the US. In addition, on 28 June 2022, the US Department of Health and Human Services (HHS) announced a vaccination strategy against the monkeypox virus to be implemented across the country.

In the present study, the team reported a patient residing in Washington, USA, who was infected with the monkeypox virus. However, he was successfully vaccinated against smallpox with the ACAM2000 smallpox vaccine eight years before. The patient was a 34-year-old male who reported having sex with men. He walked into a sexually transmitted infections clinic with a four-day history of malaise, fatigue, and headache with a two-day history of four painless penile lesions.

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